DARC Phase 1 Extension Study

• Research type

  Research Study

• Full title

  DARC Phase 1 - Extension Study:Can DARC predict glaucoma progression?

• IRAS ID

  219070

• Contact name

  Eduardo Normando

• Contact email

  e.normando@ucl.ac.uk

• Sponsor organisation

  University College London

• Duration of Study in the UK

  0 years, 3 months, 1 days

• Research summary

  The DARC Extension Study will seek to analyse the followup data of 8 consenting participants from the Glaucoma cohort who have completed original DARC Phase 1 study (a randomized Phase I, Storer Design, open-label, cross-sectional, single site trial of ANX776 in healthy volunteers, progressive glaucoma/glaucoma-suspect/ocular hypertensive subjects;15/LO/00870) for health outcomes. The purpose is to assess the validity of DARC as a surrogate marker of progressive and active glaucomatous disease using conventional measures or clinical outcomes.

• REC name

  London - Bromley Research Ethics Committee

• REC reference

  17/LO/0429

• Date of REC Opinion

  28 Feb 2017

• REC opinion

  Favourable Opinion