D-serine as a potential biomarker for schizophrenia
Research type
Research Study
Full title
D-serine as a potential biomarker for schizophrenia
IRAS ID
218556
Contact name
Jonathan Cavanagh
Contact email
Sponsor organisation
NHS Greater Glasgow and Clyde
Duration of Study in the UK
0 years, 2 months, 1 days
Research summary
Currently we do not have markers in blood or urine that can act as a test for various types of mental health problems. Recent research has shown that the body’s immune and inflammation responses may be different in mental disorders from those who do not suffer from these symptoms. We want to explore whether measuring markers of these responses in blood and urine can help identify people with mental health problems from people who do not have these symptoms. This study aims to increase knowledge in this area by investigating levels of d-serine urine samples from people with a confirmed diagnosis of schizophrenia and compare to healthy controls. It will also be investigated whether low d-serine levels are associated with high levels of inflammatory markers in peripheral blood. Blood sample, urine sample and routine health data will be collected from up to 25 patients by the research team in a single study visit.
REC name
London - Fulham Research Ethics Committee
REC reference
17/LO/0645
Date of REC Opinion
27 Apr 2017
REC opinion
Further Information Favourable Opinion