D-RISC-ii
Research type
Research Study
Full title
Direct Retinal Imaging for Shock Resuscitation in Critical Ill Adults- II (D-RISC-ii)
IRAS ID
314354
Contact name
David Griffith
Contact email
Sponsor organisation
University of Edinburgh
Clinicaltrials.gov Identifier
NA, NA
Duration of Study in the UK
1 years, 0 months, 1 days
Research summary
This is an observational study designed to characterise the appearance of the human retina during critical illness using a special non-invasive bedside technique called optical coherence tomography (OCT) and to assess whether these appearances are affected by diagnosis, balance of fluid inputs and outputs (routinely measured in critically ill patients) , and blood pressure. Patients requiring treatment in an ICU or HDU environment (patients who are "critically ill") will be eligible provided they are ill enough (determined by their "Level of Care"), and don't have any exclusion criteria (e.g. there are contra-indications to the imaging technique, or they are so sick that they are likely to die). Patients will undergo 2 bedside retinal scans which will be conducted by members of the study team. These scans are non-invasive, and other than the potential (but very small) risk of instilling eye drops into the eye (routinely given for eye examinations in other settings), the procedure is risk free. Scans will be saved and transferred to scientists in the University of Edinburgh for analysis. Clinical data will be collected by the study team, anonymised, and matched with analysed imaging data for later analysis within the University of Edinburgh.
REC name
Scotland A: Adults with Incapacity only
REC reference
22/SS/0055
Date of REC Opinion
30 Aug 2022
REC opinion
Further Information Favourable Opinion