Cutaneous Structure and Function of the Menopausal Hot Flush

• Research type

  Research Study

• Full title

  The Menopausal Hot Flush: Cutaneous Vascular and Sudomotor Function and Structure in Symptomatic Women

• IRAS ID

  310834

• Contact name

  David Low

• Contact email

  D.A.Low@ljmu.ac.uk

• Sponsor organisation

  Liverpool John Moores University

• Duration of Study in the UK

  2 years, 1 months, 31 days

• Research summary

  The aim of this research is to 1) test how the skin blood vessels and sweat glands function in women who experience hot flushes by using skin microdialysis to deliver small amounts of substances to the skin that cause increased skin blood flow and sweating, and 2) examine the structure of the skin blood vessels and sweat glands in the skin of women who experience hot flushes by taking a very small skin biopsy. Any changes in the function or structure of the skin blood vessels or sweat glands in women with hot flushes would increase our understanding of what causes hot flushes and help to design effective treatments.

• REC name

  North West - Greater Manchester South Research Ethics Committee

• REC reference

  22/NW/0300

• Date of REC Opinion

  24 Oct 2022

• REC opinion

  Further Information Favourable Opinion