CT Guided WiSE-CRT
Research type
Research Study
Full title
Image Optimisation and Guidance for Wireless Endocardial Cardiac Resynchronisation Therapy: The CT Guided Trial
IRAS ID
239322
Contact name
Steven Niederer
Contact email
Sponsor organisation
King's College London
Duration of Study in the UK
2 years, 0 months, 1 days
Research summary
This research study will aim to use computer tomography (CT) to help guide and optimise the placement of the WiSE-CRT device. This is a device that is used to treat patients with symptomatic severe heart failure. It works by making both sides of the heart beat in synchrony which improves patient symptoms and well-being. Currently, the device is placed within the left side of the heart at random locations. We will use CT scanning to identify the best locations to place the device within the heart which we hope might improve patient outcomes even further.
The WiSE-CRT device is made up of a transmitter, battery and electrode. The transmitter is placed under the skin and attached to the battery. The transmitter sends a signal to the electrode when it detects the right side of the heart beating. The electrode (placed inside the left side of the heart) receives this signal and causes the left side of the heart to beat. Effectively, this causes both the right and left sides of the heart to beat together. Currently, we have no way to know where is best to place the electrode and transmitter. Ideally it would be best to target the healthies areas of heart and avoid damaged or scarred areas. We hope by using CT scanning we can target this optimal location to enable patients to have a better overall response.
REC name
London - Harrow Research Ethics Committee
REC reference
18/LO/0752
Date of REC Opinion
24 Jul 2018
REC opinion
Further Information Favourable Opinion