Crohn’s Disease Whole Genome Epistasis Analysis
Research type
Research Study
Full title
Crohn’s Disease Whole Genome Epistasis Analysis Based on a New Multivariate Mathematical Method.
IRAS ID
309543
Contact name
Justyna Kozlowska
Contact email
Sponsor organisation
C4X Discovery Ltd
Duration of Study in the UK
1 years, 0 months, 1 days
Research summary
C4X Discovery Ltd is a company based in the UK. Our goal is to develop new and more effective medicines for disorders such as Crohn's Disease. We do that by analysing genetic data in a different way than classical methods. Our method is able to identify patterns in the genetic data that can explain different disease sub-types. We have applied our method to a Crohn’s Disease genetic dataset that was made available to us in the UK. We discovered three potential disease sub-types, each having specific genetic susceptibilities. We would like to confirm and explore further these very interesting results on a US dataset.
REC name
North East - Newcastle & North Tyneside 2 Research Ethics Committee
REC reference
21/NE/0232
Date of REC Opinion
25 Jan 2022
REC opinion
Further Information Favourable Opinion