CRICKET: CRT Improved Clinical Response UK Trial
Research type
Research Study
Full title
The Cardiac Resynhronization Improved Clinical Response UK Trial (CRICKET): a multi-centre, prospective, randomized, cross-over, double blind study
IRAS ID
190522
Contact name
Francisco Leyva
Contact email
Sponsor organisation
Aston University
Clinicaltrials.gov Identifier
Duration of Study in the UK
2 years, 9 months, 1 days
Research summary
Whilst we know that pacemaker treatment of heart failure, so-called cardiac resynchronisation therapy (CRT), is very effective, not all patients respond to the treatment. We also know that patients who do improve can improve further with programming the CRT device in different ways. The purpose of this research study is to find which programme can make the CRT devices more effective.
Cardiac resynchronisation, which is what the pacemaker provides, treats the incoordination of contraction of the heart muscle with electrical impulses that are timed in a particular fashion. How this is done depends on the way the device is programmed. In this study, we shall be comparing two different ways of programming the device.
REC name
East Midlands - Leicester Central Research Ethics Committee
REC reference
16/EM/0121
Date of REC Opinion
12 Apr 2016
REC opinion
Favourable Opinion