CPinMS
Research type
Research Study
Full title
Role of C. perfringens epsilon toxin in multiple sclerosis
IRAS ID
170844
Contact name
Rick Titball
Contact email
Duration of Study in the UK
1 years, 3 months, 1 days
Research summary
This study is using serum samples that have already been collected during other ethically approved studies. Serum is the part of blood that contains the proteins that tell us about the body's immunity and what bacteria a person has been infected by. The serum required is that of healthy people and those who have been diagnosed with multiple sclerosis. The point of this research is to see if people with multiple sclerosis are more likely to have been developed an immune response to a toxin produced by Clostridium perfringens. The reason that we are doing this is that there is a very small body of evidence in the USA that suggests that Clostridium perfringens may be associated with the development of multiple sclerosis and we would like to look at samples in the UK to see if samples from people with MS are more or less likely to show signs of C. perfringens infection.
REC name
HSC REC B
REC reference
15/NI/0101
Date of REC Opinion
22 May 2015
REC opinion
Favourable Opinion