Cough frequency and patterns in children.

• Research type

  Research Study

• Full title

  Cough frequency and patterns in children with different respiratory diseases.

• IRAS ID

  183111

• Contact name

  Deblej Elghamoudi

• Contact email

  Deblej.elghamoudi@postgrad.manchester.ac.uk

• Duration of Study in the UK

  1 years, 6 months, days

• Research summary

  Cough is extremely common in children in most respiratory diseases, such as asthma, cystic fibrosis, and primary ciliary dyskinesia. We know little about the cough frequency and the pattern of cough (time of day, single coughs, bouts of coughing) in different respiratory diseases and how this changes when children are well and unwell (infections etc). We can ask people how their cough affects them but people perceive this in different ways. Recording coughs will give us accurate measures of cough frequency and pattern between different diseases.
  We have recently been using a cough recording device (Vitalojak) in children and found most children happy to wear it for up to 24 hours without any problems. From this we are able to accurately tell how often a child coughs and also look at patterns of coughing (time of day, numbers of coughs in a row etc). We would hope this study will give us valuable information as to what the normal coughing rates and patterns are in these diseases. The study will be divided into three groups: cystic fibrosis group, asthma group, and primary ciliary dyskinesia group, each group divided into two phases: acute exacerbation phase and stable phase. The aim is to recruit 20-40 patients during acute exacerbation and stable phase in each disease presenting as either an inpatient or outpatient . On two occasions (acute and stable period of the disease), all subjects will wear the VitaloJAK cough monitor for up to 24 hours, the child and their parents will complete a generic quality of life questionnaire, a cough specific quality of life questionnaire, Visual Analogue Score for daytime and night-time cough, and answer a few questions about their cough. The cough recordings will be uploaded to a secure server hosted by the University of Manchester and analysed by researcher.

• REC name

  North West - Preston Research Ethics Committee

• REC reference

  15/NW/0612

• Date of REC Opinion

  18 Aug 2015

• REC opinion

  Further Information Favourable Opinion