Correlation of deep endometriosis and pelvic pain
Research type
Research Study
Full title
Correlation of deep endometriosis and pelvic pain
IRAS ID
253310
Contact name
Davor Jurkovic
Contact email
Sponsor organisation
University College London
Clinicaltrials.gov Identifier
Z6364106/2018/12/45 , Data protection number
Duration of Study in the UK
2 years, 0 months, 1 days
Research summary
Endometriosis is a common gynaecological condition. It occurs when tissue similar to the inner lining of the womb (endometrium) is found elsewhere, usually around the womb, ovaries and fallopian tubes, but sometimes also in the bladder and bowel. It is thought to be present in up to 40% of women. It can cause a wide range of pain symptoms, including menstrual and non-menstrual pelvic pain, pain during sexual intercourse, pain when opening bowels and when passing urine. These symptoms can be debilitating and have a major negative impact on womens’ quality of life. However, some women with endometriosis are well and not suffering from any pain.
Endometriosis is still a poorly understood condition. We would like to find out more about why some women with deep endometriosis have severe pain symptoms, whereas others are completely symptom-free. We would also like to better understand the effect of endometriosis on womens’ quality of life.
We are looking to invite women who attend our outpatient gynaecology clinic to join our study. They will be asked to complete a questionnaire, to give us a better understanding of their symptoms and quality of life. They will then receive a pelvic ultrasound scan (as per routine care). This should help us to better understand the association between different pelvic pain types and deep endometriosis in different locations within the pelvis. These findings are expected to be beneficial in counselling, further investigation and management of women who present with pelvic pain symptoms.
The questionnaire will take up a few extra minutes of patients' time in our clinic, but the study will not require any further intervention beyond this.
REC name
North West - Liverpool Central Research Ethics Committee
REC reference
19/NW/0050
Date of REC Opinion
22 Jan 2019
REC opinion
Favourable Opinion