CONTRADIA (V1.0-04.04.2017)
Research type
Research Study
Full title
Effects of concurrent resistance exercise and high-intensity interval exercise training on skeletal muscle adaptations in individuals with type 2 diabetes mellitus
IRAS ID
220012
Contact name
Myra Nimmo
Contact email
Sponsor organisation
The University of Birmingham
Duration of Study in the UK
0 years, 6 months, 24 days
Research summary
It is recommended that individuals perform a combination of resistance exercise and endurance exercise. Lack of time is often cited as a reason for being unable to meet current exercise guidelines. Therefore, combining both forms in one session may be beneficial. However, research continues to elucidate whether interference of adaptive outcomes occurs when resistance exercise and endurance exercise are performed concurrently. A proposed interference effect suggests that concurrent training may dampen resistance exercise-induced adaptations (e.g., muscle strength and growth) compared to resistance training only.
We propose to investigate the effects of concurrent resistance training and HIIT, compared to resistance training only, on muscle health and cardiovascular risk in sedentary, middle-aged (40-65 years) who are overweight/obese with type 2 diabetes mellitus. We will measure the effects on muscle strength, muscle growth, cardiovascular fitness, glycaemic control and markers of cardiovascular risk before and after an 8-week training program. Data will be obtained through the analysis of skeletal muscle samples, blood samples, magnetic resonance imaging, questionnaires and exercise performance tests.
A finding that concurrent resistance training and HIIT does not impede muscle adaptations could offer future strategies to minimise exercise time commitment whilst still maximising the physiological benefits of both resistance and endurance exercise through a single training session. This may therefore provide an effective exercise strategy in the prevention and/or treatment of type 2 diabetes mellitus.
REC name
West Midlands - Black Country Research Ethics Committee
REC reference
17/WM/0171
Date of REC Opinion
10 May 2017
REC opinion
Further Information Favourable Opinion