Continuous Intravascular Glucose Monitoring in Neurocritical Care
Research type
Research Study
Full title
Continuous Intravascular Glucose Monitoring in Neurocritical Care: Validation and Correlation
IRAS ID
227831
Contact name
Ari Ercole
Contact email
Sponsor organisation
Cambridge University Hospitals Research & Development
Clinicaltrials.gov Identifier
Duration of Study in the UK
1 years, 0 months, 0 days
Research summary
Control of glucose levels is important in critically unwell patients, particularly so in patients with brain injury. This study uses a new device to measure levels of glucose in the blood stream, by showing a real time glucose level. This device is held in a normal cannula (plastic tube) which is inserted routinely for most patients attending hospitals.
The primary purpose of the project is to confirm that this device is accurate in this patient group, by comparing glucose values to the values which we normally measure in neurocritical care. The secondary purpose is to then use the real time monitoring of the device, and compare glucose levels in the blood to glucose levels in the injured brain, and to observe the relationship between the two. We also will observe how routine medications or procedures on neurocritical care affect blood glucose levels, and whether brain glucose levels are affected in the same way. Eligible patients will have sustained a brain injury which will require care on our specialist neurocritical care unit and need monitoring of their brain with a probe as part of their usual care. Then, during their stay, we will insert the device through a cannula for a period of 72 hours, before removing it. This will be at one large teaching hospital, and only on the neurocritical care unit.
The project hopes to validate a device for accurate use in the care of this patient group, so we can better monitor and regulate their glucose levels, as well as to gain a better understanding of how blood and brain glucose interact in order to understand how we can best control it to improve outcomes for patients with brain injury.REC name
Yorkshire & The Humber - Bradford Leeds Research Ethics Committee
REC reference
18/YH/0016
Date of REC Opinion
13 Feb 2018
REC opinion
Further Information Favourable Opinion