ContinUous behavioural Biomarkers Of cognitive Impairment (CUBOId)
Research type
Research Study
Full title
ContinUous behavioural Biomarkers Of cognitive Impairment (CUBOId) – behavioural analysis through multisensory data fusion at home to assess people with cognitive impairment and early dementia.
IRAS ID
234027
Contact name
Yoav Ben-Shlomo
Contact email
Duration of Study in the UK
2 years, 0 months, 1 days
Research summary
There is a pressing need to characterise the development and progression of cognitive decline at a time many years prior to a dementia diagnosis in order that treatments can be targeted early to maintain quality of life. The CUBOId proposal leverages a national investment of £12 million in the EPSRC Sensor Platform for HEalthcare in a Residential Environment (SPHERE) Interdisciplinary Research Collaboration. This aims to greatly advance the state of the art in using new technologies for monitoring many different health-related behaviours in peoples' home.
The CUBOId project is a feasibility or "proof of concept" study. CUBOId’s team will develop new computer methods that can analyse routine behaviours that individuals do whilst going about their daily activities. By looking at these data over time, we hope to spot patterns ("signatures") that may indicate early problems with memory and other features related to mild cognitive impairment and future risk of developing dementia. We also want to see if these are much more sensitive indicators of progression and how they change when patients are given existing drugs for dementia. In this way we hope to develop new methods that can be used by other researchers in the UK Dementias Research Institute and also applied to cohorts in the Dementias Platform UK (DPUK) consortium as well as internationally.
REC name
Wales REC 7
REC reference
18/WA/0158
Date of REC Opinion
18 Jun 2018
REC opinion
Further Information Favourable Opinion