ConCIPS Study
Research type
Research Study
Full title
ReCONstruction of three-dimensional Electroanatomical Activation Maps using a Novel Electrocardiographic imaging technique: the Cardiac Isochrone Positioning system (CIPS) - the ConCIPS study
IRAS ID
234465
Contact name
Francisco Leyva
Contact email
Sponsor organisation
University Birmingham NHS Trust
Duration of Study in the UK
2 years, 0 months, 1 days
Research summary
Introduction
The recording of electrical signals transmitted from the heart to the body surface is fundamental to the generation of an electrocardiogram (ECG). This simple procedure has been at the cornerstone of modern cardiology, allowing the diagnosis and management of a wide variety of heart disorders. However, in the failing heart, there are often complex changes that occur in the electrical activation of different regions within the heart and these are poorly depicted on a standard ECG.
Aims
In this single-center, prospective study, we aim to asses the feasibility and accuracy of a new computer-based algorithm, termed the Cardiac Isochrone Positioning System (CIPS). This novel anatomical reconstruction software can generate three-dimensional (3D) "maps" of electrical activity in the heart, by combining a standard 12-lead ECG tracing (electrical tracing of the heart obtained from electrodes placed onto the chest) alongside patient-specific anatomical information obtained from MRI/CT imaging. We aim to generate and contrast these 3D maps in subjects with normal and abnormal electrical conduction.
What we will do
We will recruit a total of 150 subjects from a single hospital center. Those selected will have previously undergone a standard electrical tracing of their heart (ECG). Patients will be placed into five groups depending on the findings from this ECG, with 25 subjects in each group. One group will represent those with "normal" electrical conduction.
Recruited participants will be asked to attend an outpatient clinic. A study physician will obtain a simple electrical tracing of the heart (ECG) by placing electrodes onto the body surface (chest). The position of these electrodes will be photographed with the use of a specialized 3D camera (KINECT). This will then be translated into a three-dimensional reconstruction of electrical activation of the heart using computer software.
It is anticipated that patients will only require one hospital visit.
REC name
West Midlands - Black Country Research Ethics Committee
REC reference
18/WM/0029
Date of REC Opinion
7 Mar 2018
REC opinion
Further Information Favourable Opinion