Computed Tomography assessment of Regional Ventilation (CURVE)

• Research type

  Research Study

• Full title

  An observational study of non contrast computed tomography in assessment of regional ventilation of the lung.

• IRAS ID

  178070

• Contact name

  Babu Naidu

• Contact email

  babu.naidu@heartofengland.nhs.uk

• Sponsor organisation

  Heart of England NHS Foundation Trust

• Duration of Study in the UK

  2 years, 0 months, 1 days

• Research summary

  CT scans without contrast injections will be performed after patients breathe in and breathe out. The data obtained will be analysed using computer software to calculate how the volume of air in the lung tissue changes with breathing. The change in air volume differs throughout the lung and is a marker of how well ventilated each part of the lung is. This may help us predict changes in lung ventilation after surgery. The ventilation pattern may also help diagnose or track progression of lung diseases if the pattern is shown to be characteristic of a specific disease. The data will be anonymised and patients already routinely undergo CT scanning prior surgery and as part of diagnosis for lung diseases.The scans do not require any physical contact with the patient or injections.
  We will also give patients a questionnaire about any existing breathlessness and complete standard lung function tests (spirometry and gas transfer).

• REC name

  East Midlands - Nottingham 1 Research Ethics Committee

• REC reference

  15/EM/0446

• Date of REC Opinion

  23 Nov 2015

• REC opinion

  Further Information Favourable Opinion