Comparison of two aspheric intraocular lenses for micro-monovision
Research type
Research Study
Full title
A randomised, controlled study to compare visual performance at distance, intermediate and near, refractive outcome, contrast sensitivity, stereoacuity, patient satisfaction and patient related health economics following bilateral, micro-monovision insertion of two monofocal, aspheric, hydrophobic acrylic intraocular lenses: The TECNIS Eyhance® ICB00 and the Alcon IQ SN60WF lenses.
IRAS ID
315330
Contact name
Scott Robbie
Contact email
Sponsor organisation
Guy's & St Thomas' Foundation NHS Trust,
Duration of Study in the UK
1 years, 8 months, 31 days
Research summary
In an aging population, cataract and presbyopia become increasingly common. A cataract develops when the natural crystalline lens inside a person’s eye, becomes cloudy over time, causing reduction of vision. Presbyopia is an age related condition resulting in loss of reading/near vision and requiring reading glasses.
Cataract surgery is the most common elective surgery in the world for patients over 65. It is composed of removal the cataract and insertion of a new intraocular lens (IOL). Currently only monofocal IOLs are available on the NHS – meaning they give good distance or near vision. The majority of patients opt for good distance vision with glasses to read.
We are trialling insertion of a new Extended Depth of Focus (enhanced aspheric) IOL (EDoF IOL), which treats both cataract and presbyopia. All patients attending St Thomas’ hospital for treatment of cataracts will be considered for invitation to the study.
Patients who participate in the study will be randomly selected to receive either the new Extended Depth of Focus IOL – the TECNIS Eyhance ICB00 IOL, or a well-established monofocal (non-EDoF) IOL the Alcon Acrysof IQ SN60WF IOL during cataract surgery. Insertion of the Alcon Acrysof IQ SN60WF IOL is known to treat cataract but not presbyopia.
Patients will be assessed and have their surgery performed at St Thomas’ Hospital London. They will have 7 appointments over 12 months, plus surgery. We hope to demonstrate better distance, intermediate and near vision and increased spectacle independence in the TECNIS Eyhance ICB00 IOL group.
EDoF IOLs have the potential to improve cataract surgery outcomes for patients in the NHS.
REC name
London - Dulwich Research Ethics Committee
REC reference
22/LO/0498
Date of REC Opinion
10 Aug 2022
REC opinion
Further Information Favourable Opinion