Comparison of aspheric toric intraocular lenses for micro-monovision
A randomised, controlled study to compare visual performance at distance, intermediate and near, refractive outcome, contrast sensitivity, stereoacuity, patient satisfaction, patient related health economics and rotational lens stability following bilateral, micro-monovision insertion of two toric, aspheric, hydrophobic acrylic intraocular lenses: The TECNIS Eyhance Toric II IOL and the Alcon Acrysof IQ Toric IOL
Guy's & St Thomas' Foundation NHS Trust,
Duration of Study in the UK
1 years, 8 months, 31 days
In an aging population, cataract and presbyopia become increasingly common. A cataract is the opacification of the natural crystalline lens inside a person’s eye, causing reduction of vision. Presbyopia is an age related condition resulting in loss of reading/near vision which results in requiring reading glasses.
Astigmatism is a common condition characterized by an abnormal cornea (the clear tissue at the front of the eye) which results in blurred distance and near vision, again requiring glasses.
Cataract surgery is the most common elective surgery worldwide for patients over 65. It is composed of removal the cataract and insertion of a new intraocular lens (IOL). Currently only monofocal IOLs are available on the NHS – meaning they give good distance or near vision. The majority of patients opt for good distance vision with glasses to read.
We are trialling insertion of a new Extended Depth of Focus (enhanced aspheric) Toric IOL (EDoF Toric IOL), which treats all 3 conditions – cataract, presbyopia and astigmatism. All patients attending St Thomas’ hospital for treatment of cataracts, who have presbyopia and astigmatism will be considered for invitation to the study.
Patients who participate in the study will be randomly selected to receive either the new IOL – the TECNIS Eyhance Toric II IOL, or a well-established IOL the Alcon Acrysof IQ Toric IOL during cataract surgery. Insertion of the Alcon Acrysof IQ Toric IOL is known to treat cataract and astigmatism but not presbyopia.
Patients will be assessed and have their surgery performed at St Thomas’ Hospital London. They will have 7 appointments over 12 months, plus surgery. We hope to demonstrate better distance, intermediate and near vision and increased spectacle independence in the TECNIS Eyhance Toric II IOL group.
EDoF Toric IOLs have the potential to transform cataract surgery outcomes for patients in the NHS.
South Central - Oxford B Research Ethics Committee
Date of REC Opinion
8 Jun 2022
Further Information Favourable Opinion