Comparing Single Breath Count and Forced Vital Capacity
Research type
Research Study
Full title
Is there a positive correlation between Single Breath Count and Forced Vital Capacity in a healthy adult population?
IRAS ID
266206
Contact name
Rajiv Mohanraj
Contact email
Sponsor organisation
Salford Royal NHS Foundation Trust
Duration of Study in the UK
0 years, 3 months, 28 days
Research summary
Why?
Assessing Forced Vital Capacity (FVC) with spirometry is currently the gold standard monitoring tool used in patients with neuromuscular weakness. Unfortunately FVC is not always available in hospitals or it cannot be performed due to technical reasons.
Single Breath Count (SBC) can be used as an alternative to FVC. However there is no study that directly compares SBC and FVC.What?
We hypothesise that in a healthy adult population there is a strong correlation between SBC and FVC.Who and Where?
We are planning to approach staff and visitors in the Neurology department in Salford Royal NHS Foundation Trust. Adults over 16 years old will be eligible if they do not have any significant comorbidity, active asthma and are able to use the spirometry mouthpiece.How?
1) We will take consent in a separate room, which will be booked in advance to avoid work disruption.
2) Study procedures (will also be carried out in a separate room for privacy of volunteers):
2a Measure height and weight.
2b Basic demographic data (age, gender) and smoking status will be recorded.
2c Brief demonstration of how to perform SBC and spirometry.
2d Single Breath Count (measured in counts): participant will take a deep breath and start counting using their usual voice at a controlled rate of 2 beats per second (we will use a metronome app on a Smartphone to aid this). Participants will then be given a minute to rest.
2e Spirometry: The FVC will be measured using a bedside spirometer. Participants will then be given a minute to rest.
2f Steps 2d and 2e will be repeated overall three times. The best result will be recorded on a pre-designed proforma. The information will then be transferred to Excel document on a hospital computer.REC name
South Central - Hampshire B Research Ethics Committee
REC reference
19/SC/0478
Date of REC Opinion
1 Oct 2019
REC opinion
Favourable Opinion