ColoCap
Research type
Research Study
Full title
ColoCap: determining the diagnostic accuracy of colon capsule endoscopy compared to standard colonoscopy in patients at risk of colorectal disease.
IRAS ID
331349
Contact name
James Turvill
Contact email
Sponsor organisation
York and Scarborough Teaching Hospitals NHS Foundation Trust
Duration of Study in the UK
2 years, 8 months, 30 days
Research summary
Patients due to attend for a colonoscopy because of suspected serious bowel disease (colitis or colorectal cancer) or for routine surveillance after polyp removal will be invited to join the study. The study is designed to be as similar to a standard colonoscopy as possible. After a day of bowel preparation, the participant will swallow the capsule under supervision, first thing in the morning and then, later that afternoon, a colonoscopy will be performed. This will allow up to 8 hours for the capsule to pass. The participant will not be able to eat during this time and so it will be a long day for participants to cope with, but it will avoid the need for two lots of bowel preparation and investigations on two separate days. This study will allow us to directly compare the capsule findings with those of the colonoscopy and so find out how accurate the capsule is at detecting bowel disease. We will also ask participants and the clinical team what their experience of the capsule has been. Finally, we shall compare the costs of the capsule over those of colonoscopy.
REC name
North East - Tyne & Wear South Research Ethics Committee
REC reference
24/NE/0178
Date of REC Opinion
31 Oct 2024
REC opinion
Further Information Favourable Opinion