Collection of venesected human blood for application in organ research
Research type
Research Study
Full title
Collection of venesected human blood for application in organ research
IRAS ID
319956
Contact name
Neil Sheerin
Contact email
Sponsor organisation
The Newcastle upon Tyne Hospitals NHS Foundation Trust
Duration of Study in the UK
4 years, 1 months, 30 days
Research summary
Our research unit wants to increase the numbers of organs available to transplant into patients. We think this could be done by repairing damage to the organs before transplant, these repaired organs could last longer and perform better. The technique we use for repairing the organs is ‘machine perfusion’. There are different types of perfusions, we mainly use normothermic perfusion, in which the warmed, blood-based fluid passes through the organ. We wish to collect blood removed from patients during routine venesection to use in our perfusion work. This would enable us to expand our perfusion work to a model using whole blood. Patients undergo venesection at Freeman Hospital for a number of physiological reasons, typically about 200 mL of blood is removed and then disposed of via clinical waste. We propose to obtain permission from the patients to collect this blood and store it at Newcastle University for use in perfusion and related work.
REC name
London - London Bridge Research Ethics Committee
REC reference
23/PR/0070
Date of REC Opinion
7 Feb 2023
REC opinion
Favourable Opinion