Collection of spine and joint tissues for research into human disease
Research type
Research Tissue Bank
IRAS ID
303358
Contact name
Daniel McWilliams
Contact email
Research summary
A study of the molecular mechanisms of various human diseases using post mortem spine and joint tissues
REC name
East Midlands - Derby Research Ethics Committee
REC reference
21/EM/0193
Date of REC Opinion
14 Sep 2021
REC opinion
Further Information Favourable Opinion
Data collection arrangements
Study data for the participants will be stored electronically and/or on paper and information on this will be filed in the Study Master File (SMF) at Sherwood Forest Hospitals NHS Foundation Trust.Relatives may be approached by the bereavement team, ward and department staff, and provided an interest in donation of tissue from the deceased is expressed, a member of the research team will be contacted by the bereavement team ward or department staff. The study will be discussed by the member of the research team, bereavement team and relatives, with written consent being invited. Discussion will include the range of tissues that may be collected and the purpose of that collection. If consent is given a copy of the signed document will be copied and retained by relatives, the Bereavement Centre, Pathology Department, and the member of the research team. The donor can withdraw their consent, without giving any reason, up to the time of that collection, by phoning the study contacts. Similarly, the donor can withdraw their consent for the continued retention and use of their relative's samples even after they have been collected, without giving a reason.Tissue harvesting will be scheduled in the mortuary and histopathology department. After an examination of the external anatomy, all tissue will be obtained through open dissection.
Research programme
The Arthritis Research UK Pain Centre at The University of Nottingham investigates the mechanisms that lead to the chronic pain experienced by sufferers of arthritis, in order to improve the treatment of that pain.
Storage license
12451
RTBTitle
A study of the molecular mechanisms of various human diseases using post mortem spine and joint tissues
Establishment organisation
University of Nottingham
Establishment organisation address
University Park
Nottingham
NG7 2UH