Collection of spine and joint tissues for research into human disease

• Research type

  Research Tissue Bank

• IRAS ID

  195898

• Research summary

  A study of the molecular mechanisms of various human diseases using post mortem spine and joint tissues

• REC name

  East Midlands - Derby Research Ethics Committee

• REC reference

  16/EM/0026

• Date of REC Opinion

  26 Feb 2016

• REC opinion

  Further Information Favourable Opinion

• Data collection arrangements

  Study data for the participants will be stored electronically and/or on paper and information on this will be filed in the Study Master File (SMF) at Sherwood Forest Hospitals NHS Foundation Trust.Relatives may be approached by the bereavement team, ward and department staff, and provided an interest in donation of tissue from the deceased is expressed, a member of the research team will be contacted by the bereavement team ward or department staff. The study will be discussed by the member of the research team, bereavement team and relatives, with written consent being invited. Discussion will include the range of tissues that may be collected and the purpose of that collection. If consent is given a copy of the signed document will be copied and retained by relatives, the Bereavement Centre, Pathology Department, and the member of the research team. The donor can withdraw their consent, without giving any reason, up to the time of that collection, by phoning the study contacts. Similarly, the donor can withdraw their consent for the continued retention and use of their relative's samples even after they have been collected, without giving a reason.Tissue harvesting will be scheduled in the mortuary and histopathology department. After an examination of the external anatomy, all tissue will be obtained through open dissection.

• Research programme

  The Arthritis Research UK Pain Centre at The University of Nottingham investigates the mechanisms that lead to the chronic pain experienced by sufferers of arthritis, in order to improve the treatment of that pain.

• Storage license

  12451

• RTBTitle

  A study of the molecular mechanisms of various human diseases using post mortem spine and joint tissues

• Establishment organisation

  University of Nottingham

• Establishment organisation address

  Research and Innovation , University of Nottingham, East Atrium, Jubilee Conference Centre, Triumph

  Nottingham

  NG8 1DH