Collection Methods 1 - Nasal Mucous

• Research type

  Research Study

• Full title

  Evaluation of Different Collection Methods for Nasal Mucous in Humans (1)

• IRAS ID

  195327

• Contact name

  David Hill

• Contact email

  David.Hill2@wales.nhs.uk

• Sponsor organisation

  University of Liverpool

• Duration of Study in the UK

  0 years, 10 months, 31 days

• Research summary

  The research question we ultimately wish to investigate is the concentration of inorganic metallic cations (i.e. calcium, magnesium, copper etc) in normal nasal mucous, prior to a later similar research project in patients with nasal disease. To study these concentrations we need to optimise the method of sampling nasal mucous in normal subjects without using dilution techniques (i.e. nasal washouts). This study will compare two different methods of passively absorbing nasal mucous onto an inert substrate.

  We plan to use normal healthy volunteers. We will use two main methods of collecting mucous. One will use a dry pledget of cotton wool placed in the nose to absorb the mucous. The other will be the placement of a plastic splint into the nose onto which the mucous will attach. Once these substrates have been removed, they will be weighed, and the amount of mucous will be calculated.

• REC name

  Wales REC 5

• REC reference

  15/WA/0455

• Date of REC Opinion

  21 Dec 2015

• REC opinion

  Favourable Opinion