• Research type

    Research Study

  • Full title

    CognoMND: An automated cognitive and behaviour assessment tool based on language (utilising automated speech recognition and machine learning)



  • Contact name

    Leslie Ing

  • Contact email

  • Sponsor organisation

    University of Sheffield

  • Identifier

    STH22559, STH Number

  • Duration of Study in the UK

    3 years, 0 months, 1 days

  • Research summary

    The aim of this study is to develop CognoMND, a fully automated online assessment tool to detect problems with thinking ability (cognition) and behaviour in people living with motor neuron disease (MND). CognoMND will offer a unique approach to testing by analysing patients’ speech patterns to detect changes to cognition and behaviour. This tool will be designed so it can be used at home by patients, without the need for direct clinician involvement.

    The technology behind CognoMND will be adapted from our existing CognoSpeak tool used in testing memory problems. The technology will be developed for use in MND patients and their caregivers to test areas of cognition that can be affected in MND, such as attention, language, and social behaviour.

    The tool will display a computer-generated human face that asks patients and caregivers questions. Spoken answers will be recorded and run through our program to look for speech patterns that indicate problems to cognition and behaviour. Changes that are detected can trigger a specialist appointment with a clinician for further assessment. The process will be fully automatic, quick and easy to use.

    At present it often takes a long time before thinking and behaviour problems are diagnosed accurately. The results of this study could feed into future clinical trials of efficacy, tolerability and feasibility of utilising CognoMND as a cognitive diagnostic aid. This in turn could allow doctors to diagnose cognitive and behavioural problems more accurately and more quickly by using this computer system to ask questions and record answers about their cognitive problems.

    We do not consider this to be a medical device as the data generated from this form will not change or diagnose patients.

  • REC name

    West of Scotland REC 5

  • REC reference


  • Date of REC Opinion

    27 Oct 2023

  • REC opinion

    Further Information Favourable Opinion