Cognitive Muscular Therapy for people awaiting knee joint replacement
Research type
Research Study
Full title
Cognitive Muscular Therapy for people awaiting knee joint replacement
IRAS ID
317409
Contact name
SJ Preece
Contact email
Sponsor organisation
University of Salford
Clinicaltrials.gov Identifier
Duration of Study in the UK
1 years, 3 months, 2 days
Research summary
Knee osteoarthritis (KOA) is a chronic long-term condition that results in pain, disability and reduced quality of life. While current guidelines focus on the use of exercises to improve strength, there is clear evidence that people with knee osteoarthritis over-activate their muscles during functional tasks. Through NIHR funding we have developed a new behavioural intervention for people with KOA- Cognitive Muscular Therapy (CMT), CMT aims to reduce overactivity of the knee muscles and change the way people react to pain. Importantly, muscle overactivity has been linked to increased pain, elevated joint loading and a more rapid rate of cartilage loss. Our pilot data suggests CMT can reduce knee osteoarthritis pain. Specifically, we observed a 69% reduction in pain in 11 patients who received six sessions of CMT. We have subsequently trained 5 NHS physiotherapists to deliver CMT and observed them deliver the intervention to 12 patients. These patients reported average improvements in pain of 85% after 7 sessions.
The proposed project will seek to understand whether CMT could provide pain relief for people on a waiting list for joint replacement. The first stage of the project will seek to understand patient’s and clinicians perceptions of knee osteoarthritis. This insight will allow us to map changes to CMT which will make it suitable for people on a waiting list for knee replacement. Once we have modified the intervention, we will recruit 48 participants from two knee replacement waiting lists in Manchester. The participants will be randomised into a treatment or a control group. The treatment group will receive seven sessions of CMT over a 14 week period. The control group will be advised to continue with their usual care. All participants will complete questionnaires at baseline and at 20 weeks. Treatment participants will be offered an interview to understand their experiences.REC name
Yorkshire & The Humber - Bradford Leeds Research Ethics Committee
REC reference
22/YH/0231
Date of REC Opinion
14 Nov 2022
REC opinion
Further Information Favourable Opinion