Cognitive functioning and adherence to treatment in ESRD

  • Research type

    Research Study

  • Full title

    Investigating cognitive functioning as an obstacle to medication and treatment adherence in patients with end-stage renal disease (ESRD)

  • IRAS ID

    207748

  • Contact name

    Daniel Lamport

  • Contact email

    d.j.lamport@reading.ac.uk

  • Sponsor organisation

    University of Reading

  • Duration of Study in the UK

    1 years, 8 months, 30 days

  • Research summary

    It has been known since the 1830s that cognitive (i.e., memory and learning) impairments accompany kidney failure, known as end-stage renal disease (ESRD). Although impairments of cognition can have a major impact on quality of life, there has been little attempt to assess this in ESRD, or to understand their nature and the practical implications this may have in the every day life of the person with kidney failure. This study focuses on memory; impairments in memory could have a significant detrimental impact on patients, with particular implications for medication and treatment adherence.

    In outline, the methods to be used are as follows:

    Tests of prospective memory (remembering actions to be performed in the future); involved in everyday tasks such as remembering to take medication at a certain time and attending doctor's appointments.

    Administration of questionnaires to assess mood, general cognitive state, IQ and ability to carry out tasks of daily living, such as cooking and shopping.

  • REC name

    HSC REC A

  • REC reference

    16/NI/0222

  • Date of REC Opinion

    11 Oct 2016

  • REC opinion

    Unfavourable Opinion