Cognitive Control in Cocaine Dependence: A Stage 1 Pilot Study
Research type
Research Study
Full title
Cognitive Control in Cocaine Dependence: A Stage 1 Pilot Study
IRAS ID
178089
Contact name
John Marsden
Contact email
Sponsor organisation
King's College London
Duration of Study in the UK
0 years, 8 months, 29 days
Research summary
Cocaine dependence is defined by strong urges (cravings) and impaired control over use of the drug. This Stage 1 pilot feasibility study aims to determine if control over cravings can be achieved using cognitive therapy techniques successfully applied in post-traumatic stress disorder (with which cocaine dependence has similarities). Therapy techniques in PTSD are based on memory re-consolidation and cognitive restructuring. We propose to adapt these to target and reduce the impact of cravings for cocaine. Our research will also assesses the acceptability of these procedures, willingness to be randomised, treatment retention and participant's feedback on our approach. If we deliver a successful pilot we will submit a formal application for support from NIHR to run a Stage 2 randomised controlled trial.
REC name
London - Fulham Research Ethics Committee
REC reference
15/LO/0656
Date of REC Opinion
12 May 2015
REC opinion
Further Information Favourable Opinion