• Research type

    Research Study

  • Full title

    Cardiovascular magnetic resonance to individualise management in patients with suspected non-ST elevation acute coronary syndromes



  • Contact name

    Jayanth R Arnold

  • Contact email

  • Sponsor organisation

    University of Leicester

  • Duration of Study in the UK

    3 years, 1 months, 31 days

  • Research summary

    Coronary heart disease is the leading cause of death and disability in the UK. A heart attack occurs when one of the arteries supplying blood to the heart becomes blocked by a blood clot. Heart attacks can be subdivided into two categories depending on whether the artery is fully or partially blocked. Patients suspected to have the latter (called non-ST elevation acute coronary syndromes or NSTE-ACS) are admitted to hospital and taken to the catheter lab to fully open the artery with a wire and stent, to prevent it becoming completely blocked. However, sometimes it is difficult to identify the site of the blockage, and in fact, many patients with a suspected heart attack will turn out not to have one. Therefore, they will have undergone an invasive procedure unnecessarily.

    We believe that by using a non-invasive scan of the heart (cardiovascular magnetic resonance, CMR), we can accurately diagnose the problem. In this way we can help improve treatment, and also avoid catheter lab treatment in the many patients who do not need it. In this way, treatment can be made more effective and more comfortable for patients. The purpose of this study is to develop and determine which is the best imaging strategy to make an accurate diagnosis.

  • REC name

    East Midlands - Leicester Central Research Ethics Committee

  • REC reference


  • Date of REC Opinion

    15 Mar 2018

  • REC opinion

    Favourable Opinion