Clinical Research Initiative in Heart Failure - Long-term follow-up
Research type
Research Study
Full title
Clinical Research Initiative in Heart Failure - Long-term follow-up
IRAS ID
262413
Contact name
John Cleland
Contact email
Sponsor organisation
University of Glasgow
Clinicaltrials.gov Identifier
1819-0072, PBPP Application ; SR170, NRS Security
Duration of Study in the UK
3 years, 6 months, 31 days
Research summary
A series of observational studies was conducted between 1994 and 2006 inviting \ni) a cross-section of the Glasgow population and \nii) patients with a known heart problem \nto have a panel of tests to assess heart function. Patients agreed to follow-up at the time of enrolment, although not explicitly by access to electronic health records. We want to find out what happened to these (consented) patients and how accurately their heart test results predicted outcome. In particular we wish to find out:-\na) death and its place and cause (most of the people screened will now be dead)\nb) hospitalisations and their duration and causes, with a special interest in heart attacks, stroke and heart failure\nc) the results of further NHS investigations (these can be obtained by linking to local electronic health records held by Greater Glasgow & Clyde Health Board)\nd) amongst patients surviving beyond 2009 (when national prescribing records became available), what medicines patients were taken. \n\nThis information will be used to describe the incidence (new-onset) of disease (especially heart disease) in those who were apparently healthy at the time of screening, how well the heart tests could predict events for those with and without known heart disease and the pathways of disease progression (for instance, NHS tests may show the patient developed heart rhythm problems or worsening heart or kidney function).\n
REC name
South West - Frenchay Research Ethics Committee
REC reference
19/SW/0158
Date of REC Opinion
7 Aug 2019
REC opinion
Favourable Opinion