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Clinical Practice Research Datalink (CPRD) Research Database

  • Research type

    Research Database

  • IRAS ID

    242149

  • Contact name

    Tarita Murray-Thomas

  • Contact email

    Tarita.Murray-Thomas@mhra.gov.uk

  • Research summary

    Clinical Practice Research Datalink (CPRD) Research Database

  • REC name

    East Midlands - Derby Research Ethics Committee

  • REC reference

    21/EM/0265

  • Date of REC Opinion

    10 Jan 2022

  • REC opinion

    Further Information Favourable Opinion

  • Data collection arrangements

    The CPRD database contains coded and anonymised data from GP practices capturing information on demographic characteristics, diagnoses and symptoms, prescriptions, vaccination history, laboratory tests, referrals to hospital and specialist care. No identifiable patient information (i.e., name, address, exact date of birth or medical notes) is collected. CPRD also provides access to securely linked healthcare datasets including hospital care and death registry data. The data linkage process is carried out by NHS Digital, the body in England able to receive identifiable information, to ensure that CPRD only receives and provides anonymised data.
    As of October 2021, over 2,000 GP practices across the UK, equating to 1 in every 4 GP practices, have chosen to share their anonymised patient data with CPRD for vital public health research. The CPRD database continues to expand as more GP practices elect to share their data with CPRD. In 2021 the Database encompasses data on over 60 million patients, of whom 16 million are registered at GP practices currently contributing data to CPRD on a daily basis.
    More information about CPRD data, the research data governance process and approved studies demonstrating how CPRD data has been used for public benefit can be found at www.cprd.com .

  • Research programme

    CPRD provides anonymised UK health data for public health research purposes including understanding the burden of disease, risk factors for disease, disease outcomes, understanding prescribing patterns, monitoring of the safety of medicines and vaccines. CPRD data are used by public health agencies, academic institutions, charitable organisations and the life science industry in the UK and internationally, for research that benefits and improves public health. Only approved researchers can access the data and research applications are subject to a rigorous research data governance approvals process. Over 2,800 peer-reviewed publications using CPRD have been published to date and research findings have informed clinical guidelines and best practice. More information on approved and published studies using CPRD data including researchers conducting the studies can be found at https://cprd.com/research.

  • Research database title

    Clinical Practice Research Datalink (CPRD) Research Database

  • Establishment organisation

    Clinical Practice Reserach Datalink (CPRD)

  • Establishment organisation address

    10 South Colonnade

    Canary Wharf

    London

    E14 4PU