CL4-2
Research type
Research Study
Full title
Collection of samples from women diagnosed with vulvovaginal candidiasis for validation of a vaginal microbiome analysis method
IRAS ID
303785
Contact name
Kate Walker
Contact email
Sponsor organisation
Gedea Biotech AB
Duration of Study in the UK
0 years, 2 months, 31 days
Research summary
Vaginal infection affects a huge majority of women at some point in their life. The vaginal microflora maintains a weakly acidic environment and changes to vaginal microflora increase the pH, thereby forming a favourable environment for vaginal pathogens.
Additionally, vaginal or systemic antibiotics treatment is frequently followed by
vulvovaginal candidiasis (VVC), i.e. fungal overgrowth.Confirmation of a clinical diagnosis of VVC is usually done by culture but DNA sequencing may be an alternative way.
Changes in the vaginal microbiome during a VVC infection is an important component of this disease and studying it will assist in the development of novel treatments.
REC name
London - Bromley Research Ethics Committee
REC reference
21/PR/1454
Date of REC Opinion
24 Nov 2021
REC opinion
Further Information Favourable Opinion