CIRCA Chronotype and Stroke Registry
Research type
Research Study
Full title
The CIRCA Chronotype and Stroke Registry: A Multicenter Study of the Association of Chronotype with Presentation, Course, and Outcome of Acute Cerebral Ischemia
IRAS ID
338982
Contact name
Joyce S Balami
Contact email
Sponsor organisation
Sheffield Teaching Hospitals NHS Foundation Trust
Duration of Study in the UK
3 years, 1 months, 1 days
Research summary
Different studies have demonstrated that circadian/diurnal rhythms exert substantial influence on the occurrence, initial severity, acute progression, and long-term outcome of acute cerebral ischaemia.
To our knowledge, no study to date has investigated the relationship of patient’s natural sleep patterns, known as "chronotype," on ischaemic stroke severity and outcomes in either adults or children. The goal of this study is to figure out how patients’ natural sleep patterns, known as "chronotype," affect the course of stroke and stroke treatment. Some people are more active and alert in the morning (morning persons), some in the evening (night persons) and others in between.
Data on individual patient chronotype will be systematically collected from both adults and children experiencing ischaemic stroke. Participants will be asked one question about recent travel and eight questions about the times the adult or child falls asleep and wakes up. The answers will be combined with data from the patient’s medical record. The data, including hospital admission date, will be entered into the study database. All major identifiers, such as you and your child’s name and your child’s medical record number, will be removed before data entry.The knowledge from this study may improve understanding of symptomatic acute cerebral ischaemic events (stroke) and help future patients and society.
REC name
London - City & East Research Ethics Committee
REC reference
24/PR/0350
Date of REC Opinion
16 May 2024
REC opinion
Further Information Favourable Opinion