CIP/CIM in children and young people, version 2

  • Research type

    Research Study

  • Full title

    Prospective and retrospective study of clinical features and outcomes of critical illness polyneuropathy and/or myopathy in children and young people, Version 2

  • IRAS ID

    358225

  • Contact name

    Sithara Ramdas

  • Contact email

    sithara.ramdas@ouh.nhs.uk

  • Sponsor organisation

    Oxford University Hospitals NHS Foundation Trust

  • Duration of Study in the UK

    2 years, 11 months, 31 days

  • Research summary

    Critical illness polyneuropathy and myopathy (CIP/CIM) are rare disorders seen in patients admitted with severe illness to intensive care. They occur both in children and adults. Patients have severe muscle weakness (paralysis) which prolongs hospital stay and many do not recover fully. The underlying reason for this is still not fully understood. Several large studies have looked into CIP/CIM in adults including long-term outcomes but this information is lacking in children. This study will aim to gather information to better understand the risk factors and long-term outcomes in children and young people with CIP/CIM to better inform clinicians, patients and families about this rare disorder.

  • REC name

    South Central - Hampshire A Research Ethics Committee

  • REC reference

    25/SC/0395

  • Date of REC Opinion

    30 Jan 2026

  • REC opinion

    Further Information Favourable Opinion