CIN2 Monitoring using Patch sampling
Research type
Research Study
Full title
Monitoring of Cervical lesions at Colposcopy using a novel non-invasive technique for monitoring of CIN2 lesions (a pilot/ feasibility study)
IRAS ID
272534
Contact name
Robin Crawford
Contact email
Sponsor organisation
Cambridge University Hospitals NHS Foundation Trust and the University of Cambridge
ISRCTN Number
ISRCTN30282356
Duration of Study in the UK
1 years, 6 months, 1 days
Research summary
This study is being done to improve our management of women that are diagnosed with Cervical Intraepithelial Neoplasia grade 2 (CIN2). In the past this condition was treated by removal of the disease. However as we have learnt more about this condition we now know that the majority of these cases resolve spontaneously. This has meant that these women can be offered a watchful waiting approach/ expectant management approach. Indeed there has been much work that has now led to clinicians advocating for conservative management. Our approach, due to its non-invasive aspect, enables us to monitor these lesions at a molecular level without the need for a biopsy. This means that such women can be effectively managed in the community without the requirement for an intrusive exam/ test.
REC name
East of England - Cambridgeshire and Hertfordshire Research Ethics Committee
REC reference
20/EE/0082
Date of REC Opinion
4 May 2020
REC opinion
Further Information Favourable Opinion