CIMREAL

  • Research type

    Research Study

  • Full title

    A Multicenter, non-interventional, prospective study to assess the effectiveness of certolizumab pegol in patients with moderate to severe plaque psoriasis in daily practice (CIMREAL)

  • IRAS ID

    269550

  • Contact name

    Philip Laws

  • Contact email

    philip.laws2@nhs.net

  • Sponsor organisation

    UCB Bioscience GmbH

  • Clinicaltrials.gov Identifier

    243324, Parexel ref

  • Duration of Study in the UK

    2 years, 5 months, 31 days

  • Research summary

    Psoriasis (PSO) is a common, chronic inflammatory skin disease. In addition to the impact on skin, PSO has a multitude of psychosocial and emotional effects on patients, including increased self-consciousness, frustration, fatigue, depression, and suicidal ideation. As a result, patients frequently report sleeping problems, difficulties at work, problems interacting with family members, disrupted leisure activities, and sexual difficulties.

    Plaque PSO is the most common type of psoriasis, comprising approximately 80% to 90% of all cases.

    This study will look at effectiveness of Certolizumab pegol (CZP) in patients with moderate to severe plaque PSO as part of routine clinical practice.

    The study will also assess the impact of CZP on quality of life.

  • REC name

    North West - Liverpool Central Research Ethics Committee

  • REC reference

    19/NW/0555

  • Date of REC Opinion

    20 Sep 2019

  • REC opinion

    Further Information Favourable Opinion