CILIAREN - Renal Ciliopathies
Research type
Research Study
Full title
Modelling ciliopathies using 3D spheroid culture of renal epithelial cells
IRAS ID
346192
Contact name
John Sayer
Contact email
Sponsor organisation
Newcastle University
Duration of Study in the UK
4 years, 0 months, 30 days
Research summary
The study will investigate inherited disorders termed ciliopathies that give rise to multi-system disorders in childhood and adolescence. Typically patients with ciliopathies develop cystic kidney disease which results in renal failure during the first 3 decades of life. In this study we will study kidney cells isolated from the urine of patients with ciliopathies in order to understand these diseases more fully. Cells grown from urine will be cultured, examined under a microscope and treated with drugs to test mechanisms of disease and potential therapies for these diseases.
REC name
North East - Newcastle & North Tyneside 2 Research Ethics Committee
REC reference
24/NE/0144
Date of REC Opinion
4 Oct 2024
REC opinion
Further Information Favourable Opinion