CIC Study

• Research type

  Research Study

• Full title

  Corticosteroid-induced cataract in childhood steroid sensitive nephrotic syndrome

• IRAS ID

  153285

• Contact name

  Nicholas Webb

• Contact email

  nicholas.webb@cmft.nhs.uk

• Sponsor organisation

  Central Manchester University Hospitals NHS Foundation Trust

• Research summary

  The primary aim of this observational study is to ascertain the prevalence of corticosteroid-induced cataract (CIC) in the population of children with steroid sensitive nephrotic syndrome (SSNS) attending the Royal Manchester Children’s Hospital (RMCH) and its affiliated district hospitals. We will further determine the proportion of these cases that have mutations in the 113 genes known to be associated with cataract formation. The study will also document the spectrum of other ophthalmological abnormalities in this childhood population.

• REC name

  North West - Preston Research Ethics Committee

• REC reference

  14/NW/1055

• Date of REC Opinion

  7 Jul 2014

• REC opinion

  Further Information Favourable Opinion