Chronic Pain Predictors in Major Trauma- Version 1

  • Research type

    Research Study

  • Full title

    Risk factors for chronic limb pain in major trauma patients with limb injury

  • IRAS ID

    350524

  • Contact name

    Denise Kendrick

  • Contact email

    denise.kendrick@nottingham.ac.uk

  • Sponsor organisation

    University of Nottingham

  • Duration of Study in the UK

    1 years, 5 months, 28 days

  • Research summary

    A large proportion of trauma patients sustain limb injuries and it is common for people with these injuries to experience chronic pain (pain lasting for more than 3 months). Chronic pain negatively affects physical and mental health, quality of life, employment and disability. Currently, we don’t know who is most likely to develop chronic pain after traumatic limb injuries- this study aims to answer this question.
    The aim of the study is to create a risk prediction model that will identify patients at risk of developing chronic limb pain after a traumatic limb injury. The model developed in this study will help clinicians to provide clearer information to patients about their recovery. It will also help patients to access pain services more quickly.
    This study is part of a PhD which is funded by the National Institute of Health and Care Research Applied Research Collaboration (NIHR ARC) East Midlands (EM). It is a questionnaire-based study that will be completed between 2025-2027 and will recruit patients from the East Midlands Major Trauma Centre.

    The study is designed in 2 parts:
    Part 1- Testing a questionnaire which has been designed to collect information on factors that relate to chronic pain.
    Group A will complete the baseline questionnaire
    Group B will complete the three month questionnaire
    Part 2- Trauma patients with a limb injury (fracture) will complete a baseline questionnaire within four weeks of their injury. Presence, severity and impact of pain will be assessed at 3 and 6 months after injury.

    Analysis will then be carried out to see which risk factors collected in the baseline questionnaire are associated with the presence of pain at 3 and 6 months.

  • REC name

    Wales REC 4

  • REC reference

    25/WA/0273

  • Date of REC Opinion

    17 Sep 2025

  • REC opinion

    Favourable Opinion