Chronic Omega-3 Fatty Acid Supplementation in Type 1 Diabetes
Research type
Research Study
Full title
The Therapeutic Role of Chronic Omega-3 Fatty Acid Supplementation in Type 1 Diabetes Patients
IRAS ID
223639
Contact name
Matthew D Campbell
Contact email
Sponsor organisation
Leeds Beckett University
Duration of Study in the UK
2 years, 0 months, 1 days
Research summary
People with type 1 diabetes have an increased of cardiovascular disease (CVD) which significantly reduces life expectancy and quality of life. The vast majority of patients with type 1 diabetes present with blood vessel abnormalities which is heavily contribute to CVD risk and that are heavily influenced by the diet that they typically follow. Foods that are regularly consumed in westernized societies predominantly have a high fat content, which in the presence of type 1 diabetes can exacerbate CVD risk further for this cohort. Regular consumption of Omega-3 fatty acids, which are found in the diet, have been shown to reduce CVD risk factors in people with CVD and type 2 diabetes, but it is unknown whether such improvements are transferable to people with type 1 diabetes.
The research will examine factors that determine the way in which body is able to process large quantities of fat at meal times, and subsequent responses on blood vessel health following 6 months of dietary supplementation with Omega-3 fatty acids in people with type 1 diabetes. Participants will attend the laboratory on 4 occasions each separated by 3 months. Blood samples will be taken across an 8-hour period to determine and assess blood borne biomarkers, and accompanied by non-invasive scanning techniques to assess blood vessel health.
The findings from this study will aim to benefit people with type 1 diabetes by providing more refined long-term and meal-time self-management strategies.
REC name
North East - Tyne & Wear South Research Ethics Committee
REC reference
17/NE/0244
Date of REC Opinion
10 Aug 2017
REC opinion
Further Information Favourable Opinion