ChildNTP
Research type
Research Study
Full title
The Childhood N-Tidal Pilot Study
IRAS ID
225397
Contact name
A Prayle
Contact email
Sponsor organisation
The University of Nottingham
Duration of Study in the UK
0 years, 7 months, 31 days
Research summary
Children with long term lung diseases like asthma and cystic fibrosis need better techniques for monitoring their disease at home. With better monitoring, it is anticipated that children and their carers will be able to manage their disease better, and be able to spot a deterioration in their condition sooner, leading to earlier intervention, for example to prevent an asthma attack.
However, current home monitoring techniques for lung diseases are either too costly, require machines with are impractically large, or require specific breathing manoeuvres which are unpopular with patients, or which are difficult for younger children to perform. There is a need for better home monitoring techniques.
The N-Tidal is a CE Marked medical device which highly accurately measures carbon dioxide during normal breathing through a mouthpiece. Early work in its use in adult diseases such as Chronic Obstructive Pulmonary Disease indicate that the device can detect altered lung function associated with disease. This device has several attractive properties for children – it is small, easy to use, and does not require specific breathing manoeuvres – just normal breathing.
It is not known if it is feasible to use the N-Tidal the paediatric age range. Therefore in this feasibility study, as small group of children with wheeze / asthma, and cystic fibrosis will be asked to take measurements with the N-Tidal, in order to determine if measurements can be made on a routine daily basis. Data from this study will be used to plan future larger studies of the N-Tidal device in children with respiratory diseases.
REC name
West Midlands - Black Country Research Ethics Committee
REC reference
17/WM/0213
Date of REC Opinion
28 Jun 2017
REC opinion
Further Information Favourable Opinion