Childhood onset cardiomyopathies: developing risk stratification tools

  • Research type

    Research Study

  • Full title

    Childhood hypertrophic cardiomyopathy - developing a novel risk stratification tool

  • IRAS ID

    182354

  • Contact name

    Juan Pablo Kaski

  • Contact email

    j.kaski@ucl.ac.uk

  • Sponsor organisation

    Institute of Child Health (UCL)

  • Duration of Study in the UK

    3 years, 0 months, 1 days

  • Research summary

    Unexplained thickening of the heart muscle (hypertrophic cardiomyopathy or HCM) is a recognised cause of sudden cardiac death (SCD) in children. This risk can be reduced with treatment. The risk factors for SCD in adult patients are well established and high risk patients can be identified by doctors allowing treatment. In comparison, during childhood the risk factors for SCD have not been established and therefore doctors cannot reliably identify patients at high risk. This study will identify risk factors for SCD in childhood HCM and develop a tool to identify those at risk allowing treatment to be individualised for patients.

  • REC name

    West Midlands - Coventry & Warwickshire Research Ethics Committee

  • REC reference

    16/WM/0207

  • Date of REC Opinion

    21 Apr 2016

  • REC opinion

    Favourable Opinion