CHEST MI v1
Research type
Research Study
Full title
An observational study to determine the prevalence of chronic obstructive pulmonary disease and clinical outcomes in patients hospitalised for acute myocardial infarction with a significant smoking history: CHronic obstructive pulmonary diseasE in Smokers wiTh Myocardial Infarction (CHEST-MI)
IRAS ID
310223
Contact name
Robert F Storey
Contact email
Sponsor organisation
Sheffield Teaching Hospitals NHS Foundation Trust
Duration of Study in the UK
1 years, 6 months, 1 days
Research summary
Smoking is a risk factor for developing heart disease. However, it also predisposes to a range of other conditions, including lung disease. Most commonly, smoking can lead to a lung condition called chronic obstructive pulmonary disease or COPD, which can include bronchitis (irritation of the air passages) or emphysema (damage to lung tissue). These can cause cough and difficulty breathing, particularly on exercise.
Despite the fact that both heart attack and COPD are common conditions, the exact proportion of people who come into hospital with a heart attack that have COPD is not known. Whilst some patients will already have a diagnosis of COPD when they come into hospital, others may not have developed symptoms or the diagnosis may not yet have been made.
We are trying to find out the number of people that have evidence of COPD, determined by a breathing test, amongst those who come into hospital with heart attack and a history of smoking. We also want to know how the breathing test results relate to symptoms, blood results, medication and wellbeing in the year after a heart attack. This study will help when developing future work improving the care of COPD patients with heart attack.
Participants who are in hospital because of a heart attack and have a significant smoking history will be approached. After signing the consent form, their medical records will be reviewed. A breathing test known as microspirometry will be performed. They will be asked to complete a short, survey about breathing, levels of activity and energy.
At 3 and 12 months after their heart attack, we will review their medical records and telephone them check for relevant problems and to complete the short survey again.
No extra blood tests, alterations to medication or hospital visits are required as part of this study.
REC name
Yorkshire & The Humber - Bradford Leeds Research Ethics Committee
REC reference
22/YH/0015
Date of REC Opinion
6 Jan 2022
REC opinion
Favourable Opinion