Chemotherapy induced caspase activation in lymphoma
Research type
Research Study
Full title
A PET imaging study to assess the effect of chemotherapy on caspase 3/7 activation in lymphoma using the isatin sulfonamide [18F]ICMT-11.
IRAS ID
173622
Contact name
Laura Kenny
Contact email
Sponsor organisation
Imperial College London
Duration of Study in the UK
2 years, 2 months, 25 days
Research summary
Chemotherapy causes the death of cancer cells. We wish to see if a special type of scan, called a PET scan, can be used to measure cell death in patients with lymphoma a type of cancer affecting the lymph nodes. To do this we will use a a very small amount of a chemical called ICMT-11 which has a radioactive label so that the scanner can detect it in the body. We will scan patients before treatment and soon after the first treatment and compare the results to see if any change has occurred.
REC name
West of Scotland REC 3
REC reference
15/WS/0145
Date of REC Opinion
20 Aug 2015
REC opinion
Further Information Favourable Opinion