CHART
Research type
Research Study
Full title
Comprehensive geriatric assessment (CGA) to sustain independence for older people living with heart failure with preserved ejection fraction (HFpEF) and frailty: The CHART Trial
IRAS ID
345486
Contact name
Lauren Moreau
Contact email
Sponsor organisation
Bradford Teaching Hospitals NHS Foundation Trust
ISRCTN Number
ISRCTN22229432
Duration of Study in the UK
4 years, 1 months, 31 days
Research summary
Frailty is a condition that is common in older age. It develops because as we get older our bodies change and can lose their resilience. This means that older people with frailty can experience sudden, dramatic changes in their wellbeing when they have health problems. Heart failure (HF) is a complex condition where the heart muscle doesn’t pump blood as well as it should because it has become too weak or stiff. People with heart failure with preserved ejection fraction (HFpEF) have symptoms of heart failure even though their heart pumps blood well.
Current NHS services are not well developed for people who have multiple health problems. This means people with frailty and HFpEF may not receive the right sort of care they need. Comprehensive Geriatric Assessment (CGA) involves older people as well as their families, carers and healthcare professionals to identify and help manage multiple health problems and prevent new ones arising. Rehabilitation helps people to do what is important to them.
Our research aims to work out if, CGA (including rehabilitation at home) in addition to usual care helps frail older people with HFpEF maintain their ability to carry out everyday activities. This will be compared to people getting usual care alone.
We aim to recruit 433 people from 17 sites who have HFpEF and frailty. Potential participants will be invited to take part from cardiology services and followed-up by a researcher who will confirm eligibility and take consent and complete Baseline assessments. Participants in the study will be randomised to receive either CGA, 12 weeks of home-based rehabilitation, and their usual care or, their usual care only.
We will follow-up participants at 6 and 12 months after they agreed to take part and continue to collect information about them from NHS registries, such as NHS England until 24 months.REC name
Yorkshire & The Humber - Leeds East Research Ethics Committee
REC reference
24/YH/0185
Date of REC Opinion
18 Oct 2024
REC opinion
Further Information Favourable Opinion