Characteristics that predict >25% infection in liver cirrhosis

• Research type

  Research Study

• Full title

  Masters Student project: Identification of clinical and biochemical characteristics that predict >25% incidence of infection at 1 year in patients with advanced liver disease (ALD)

• IRAS ID

  236842

• Contact name

  Alastair O'Brien

• Contact email

  a.o'brien@ucl.ac.uk

• Sponsor organisation

  University College London

• Clinicaltrials.gov Identifier

  No Z6364106/2018/01/83, UCL Data protection officer ; Z6460180, Royal Free Data Protection officer

• Duration of Study in the UK

  0 years, 3 months, 24 days

• Research summary

  In patients with cirrhosis, infections represent a frequent trigger for decompensation and complications, increasing frequency of hospitalizations and mortality rate.

  This will be a descriptive retrospective study of patients admitted between 2014-2016 to The Royal Free Hospital, Chase Farm and Barnet Hospitals (classified as 1 site under the Royal Free London NHS Foundation Trust). The study's objective is to identify clinical and biochemical predictors of readmission in patients with advanced liver disease with bacterial and/or fungal infection. Every re-admission over two years for each patient will be reviewed. The clinical endpoint will be re-admission into hospital with an infection.

• REC name

  London - Surrey Research Ethics Committee

• REC reference

  18/LO/0849

• Date of REC Opinion

  31 May 2018

• REC opinion

  Further Information Favourable Opinion