Characteristics, pathways & outcomes of adults with R/R ALL

  • Research type

    Research Study

  • Full title

    A1. Characteristics, survival, treatment pathways, and healthcare resource use in adult patients with relapsed or refractory acute lymphoblastic leukaemia: a non-interventional study using secondary healthcare data from England.

  • IRAS ID

    290366

  • Contact name

    Myriam Alexander

  • Contact email

    MyriamAlexander@openvie.com

  • Sponsor organisation

    Gilead Sciences Ltd

  • Duration of Study in the UK

    0 years, 3 months, 4 days

  • Research summary

    This is a retrospective, non-interventional cohort study based on secondary use of electronic hospital medical records. This is a study on patients with acute lymphoblastic leukaemia (aLL) and relapsed/refractory acute lymphoblastic leukaemia (R/RaLL)to describe their demographics and their characteristics and clinical outcomes. This study will be conducted in the English NHS secondary settings and gaining insight from 3 cohorts, focusing on Hospital Episodes Statistics (HES), the Systemic Anti-Cancer Therapy Database (SACT) and the Cancer Registry (CR). Information will be gathered from these databases to form 3 analysis groups.\nThe population for this study is adult patients diagnosed with acute lymphoblastic leukaemia.\nThe study is based on retrospective collection of data from patients electronic medical records.

  • REC name

    South Central - Oxford B Research Ethics Committee

  • REC reference

    20/SC/0455

  • Date of REC Opinion

    31 Dec 2020

  • REC opinion

    Favourable Opinion