Characterising Vascular Cognitive Impairment. Version 1
Research type
Research Study
Full title
Characterising Vascular Cognitive Impairment.
IRAS ID
197282
Contact name
Emma Richards
Contact email
Duration of Study in the UK
1 years, 0 months, 1 days
Research summary
Characterising Vascular Cognitive Impairment - a basic science study involving patients and healthy volunteers undertaking computerized tests of visual attention and processing speed.
Evidence already shows that there are significant abnormalities in visual attention-related processing and slowed reaction time in people with Mild Cognitive Impairment and Alzheimer’s Disease (and in older compared to younger healthy adults). In this study we hypothesize that such abnormalities will also be found in those with a vascular component to their cognitive impairment, but that the effects will be significantly greater, especially in terms of speed and variability of processing. We also hypothesize the participant’s function and ability to perform the tests will vary depending on the contribution of vascular pathology.
The aim of this study is to identify the characteristics of Vascular Cognitive Impairment in relation to how people with this condition use their visual attention and how quickly they can process information. This will help us to understand how information is processed in people with Vascular Cognitive Impairment and how this relates to behaviour and current clinical characterisation.
To achieve this a range of brain functions (including those related to vision, attention, executive function, processing speed and accuracy) will be tested in people diagnosed with Vascular Cognitive Impairment and compared to performance in those with Alzheimer’s Disease/amnestic Mild Cognitive Impairment, and younger and older cognitively healthy adults using a range of iPad and computer-based tests. Testing will take approximately 90 minutes. Participants with cognitive impairment will be recruited through the memory clinic in Llandough Hospital, Cardiff.
REC name
Wales REC 6
REC reference
16/WA/0145
Date of REC Opinion
17 Jun 2016
REC opinion
Further Information Favourable Opinion