Characterising pain flares in adolescents with MKS disorders
Research type
Research Study
Full title
Characterising pain flares in adolescent inflammatory and non-inflammatory musculoskeletal disorders: A qualitative study
IRAS ID
239051
Contact name
John McBeth
Contact email
Duration of Study in the UK
2 years, 2 months, 1 days
Research summary
Adolescents with long-term musculoskeletal conditions such as juvenile idiopathic arthritis (JIA) subtypes and chronic idiopathic musculoskeletal pain syndromes (CIMPS) experience fluctuating pain that undergoes periods of exacerbation or worsening (1–5), colloquially referred to as pain ‘flares’ by patients and clinicians. These exacerbations in pain have been reported to negatively impact adolescents’ lives, including their level of confidence, identity and independence in daily living and social activities (6). It is therefore important to target interventions and treatments to reduce the frequency, severity and impact of pain flares on adolescents’ lives. However, this goal is problematic with little known about the nature and experiences of these flare.
Within this project, we propose to hold one-to-one semi-structured interviews with adolescents to explore how flares are conceptualised by this population group. Participants will be: aged 10-19 years, diagnosed with JIA or a CIMPS, under the care of a rheumatologist, have experience of pain during their disease, and do not have major cognitive or psychiatric disorder (as defined/identified by their consultant). Interviews will be conducted at Royal Manchester Children’s Hospital and will last approximately 40 minutes, but may be longer or shorter depending on how much or little adolescents would like to share. It is anticipated that the study will last no longer than 1 hour.
References:
1. Schanberg LE, Gil KM, Anthony KK, Yow E, Rochon J. Pain, stiffness, and fatigue in juvenile polyarticular arthritis: Contemporaneous stressful events and mood as predictors. Arthritis Rheum [Internet]. 2005 Apr 1 [cited 2017 Nov 1];52(4):1196–204. Available from: http://doi.wiley.com/10.1002/art.20952
2. Tupper SM, Rosenberg AM, Pahwa P, Stinson JN. Pain Intensity Variability and Its Relationship With Quality of Life in Youths With Juvenile Idiopathic Arthritis. Arthritis Care Res (Hoboken) [Internet]. 2013 [cited 2017 Nov 1];65(4):563–70. Available from: http://doi.wiley.com/10.1002/acr.21850
3. Ghaly MS, Handouka NM, Khashana AK, Shalaby SA, Fahim AE, Ramadan AE. Within-Day Variability of Pain and Its Relation to Quality of Life in Children with Juvenile Primary Fibromyalgia Syndrome. MYOPAIN [Internet]. 2015 Oct 2 [cited 2018 Jan 4];23(3-4):165–71. Available from: https://www.tandfonline.com/doi/full/10.1080/24708593.2017.1352641
4. Stinson JN, Stevens BJ, Feldman BM, Streiner D, McGrath PJ, Dupuis A, et al. Construct validity of a multidimensional electronic pain diary for adolescents with arthritis. Pain [Internet]. 2008 Jun [cited 2018 Jan 5];136(3):281–92. Available from: http://www.ncbi.nlm.nih.gov/pubmed/17723279
5. Schanberg LE, Sandstrom MJ, Starr K, Gil KM, Lefebvre JC, Keefe FJ, et al. The relationship of daily mood and stressful events to symptoms in juvenile rheumatic disease. Arthritis Rheum [Internet]. 2000 Feb 1 [cited 2017 Dec 1];13(1):33–41. Available from: http://doi.wiley.com/10.1002/1529-0131%28200002%2913%3A1%3C33%3A%3AAID-ART6%3E3.0.CO%3B2-S
6. Britton CA, Moore A. Views from the Inside, Part 2: What the Children with Arthritis Said, and the Experiences of Siblings, Mothers, Fathers and Grandparents. Br J Occup Ther [Internet]. 2002 Sep 5 [cited 2017 Dec 1];65(9):413–9. Available from: http://journals.sagepub.com/doi/10.1177/030802260206500904
REC name
South East Scotland REC 01
REC reference
18/SS/0116
Date of REC Opinion
17 Oct 2018
REC opinion
Further Information Favourable Opinion