Characterisation of eye blood vessels using OCTA V1.0
Research type
Research Study
Full title
Eye blood vessels optical coherence tomography angiography in thyroid eye disease, conjunctivitis and normal subjects.
IRAS ID
228706
Contact name
Swan Kang
Contact email
Sponsor organisation
Moorfields Eye Hospital
Duration of Study in the UK
1 years, 0 months, 0 days
Research summary
Measurement of blood flow of the eye with a new imaging technique comparing normal, thyroid eye disease and conjunctivitis subjects.
In this study, we aim to measure the blood flow of the eye using a novel new imaging technique, anterior segment optical coherence tomography angiography (AS-OCTA). AS-OCTA is a non-contact, non-invasive and rapid imaging technique that can be used to determine the blood flow in different layers of the front of the eye. In recent years, optical coherence tomography (OCT), which uses the same principle as AS-OCTA, has become an essential part of the investigation of many retinal (back of the eye) conditions including diabetic eye disease and age-related macular degeneration. It is easy and quick to use and provide important and quantitative information of the structures which are not easily visible with a traditional method of eye examination using a slit-lamp.
We will investigate if there is any difference in blood flow of the eyes of normal, thyroid eye disease and conjunctivitis patients. Thyroid eye disease is an eye condition in which the soft tissues surrounding the eye can become inflamed. This causes the eyes and eyelids to look red, bulging and swollen. Conjunctivitis also can make the eyes look red and can be caused by infection or allergies.
The study results will allow us to understand the mechanisms that cause the eyes to become red. It will provide an objective measure to grade the severity of these conditions, which will be invaluable in monitoring the response to different treatment options available.
REC name
West Midlands - Solihull Research Ethics Committee
REC reference
17/WM/0415
Date of REC Opinion
22 Dec 2017
REC opinion
Further Information Favourable Opinion