CESAR v1.0
Research type
Research Study
Full title
Contrast Enhanced mammography versus magnetic reSonance imaging for Assessing Response to neoadjuvant chemotherapy
IRAS ID
333133
Contact name
Sarah L. Savaridas
Contact email
Sponsor organisation
University of Dundee
ISRCTN Number
ISRCTN12671109
Duration of Study in the UK
2 years, 8 months, 31 days
Research summary
When patients have chemotherapy before surgery, doctors want to know how the tumour is shrinking as a result of the treatment. This helps in planning the best surgery. This is often done with magnetic resonance imaging (MRI) scans. MRI scans give very clear images but are very expensive and the patient has to lie still in the scanner for a long time which can be difficult, especially if they don’t like small spaces. Also, some patients are not able to have MRI scans if they have metal in their bodies, such as a pacemaker. (These patients are monitored using breast examination, standard mammography and ultrasound).
Recently a new type of mammogram has become available called Contrast-Enhanced Mammography (CEM) which could be used as an alternative to MRI scans. In the new technique the patient is injected with a dye which makes the cancer much easier to see than in a normal mammogram.
The aims of this research study are to compare these two different types of imaging test for breast cancer and to provide evidence for:
· Whether CEM is good enough to replace MRI scans for this purpose
· Which imaging test patients prefer
REC name
London - Bloomsbury Research Ethics Committee
REC reference
24/LO/0834
Date of REC Opinion
28 Nov 2024
REC opinion
Further Information Favourable Opinion